Учени от института Гладстоун и Университета на Калифорния в Сан Франциско са успели да превърнат човешки кожни клетки в напълно функциониращи панкреатични клетки, произвеждащи инсулин.
Новото изследване разкрива, че този нов подход към клетъчното препрограмиране не само работи, но има потенциал да се превърне в успешно лечение на хора, страдащи от диабет.
В този случай учените изпробват нова техника. Те избират човешки кожни клетки, които са изобилен и лесно достъпен източник на тъкан. Чрез използването на внимателно подбрани фармацевтични химикали, кожните клетки са преобразувани в едни по-специфични целеви клетки.
Експертите успяват да ги трансформират в панкреатични клетки, делящи се с невероятна скорост, за да станат напълно функциониращи панкреатични бета клетки. Точно те съхраняват и освобождават инсулин. За да се провери доколко са ефективни новосъздадените клетки, те са имплантирани в панкреаса на мишки. Оказва се, че те са напълно ефективни и произвеждат инсулин в отговор на нарастващите нива на глюкозата.
Учените ще продължат изследванията си върху хора, а постижението им може да се превърне в сензация в медицинския свят.
Източник: 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